Matthew WHEELER
Clinical Assistant Professor and Medical Director of the Center for Undiagnosed Diseases at Stanford University, USA

Dr. Matthew Wheeler is Clinical Assistant Professor and Medical Director of the Center for Undiagnosed Diseases at Stanford University in Stanford, California. An expert in cardiovascular genetics, he has clinical interest in advanced heart failure and inherited cardiomyopathies.  His background includes research in myocardial and skeletal muscle biology as well as molecular genetics and genomics.  He has extensive translational science experience, participating in ongoing clinical trials for hypertrophic cardiomyopathy, dilated cardiomyopathy, cardiac amyloidosis, and mechanical circulatory support.  In genetics and genomics, he has led analysis of whole genome and whole exome sequencing focusing on identifying clinically actionable rare and novel variants, first from whole genome sequecncing of a single patient and now in cohorts of inherited cardiomyopathy and undiagnosed disease patients. He is the Adult Medical Director of Stanford’s NIH-funded Center for Undiagnosed Diseases and a core member of the Undiagnosed Diseases Network.  He teaches physician and genetic counselor trainees on genomic medicine and approach to undiagnosed diseases. In addition to his work in genetics and genomics of disease, he is a member of the Bioinformatics Core of the Molecular Transducers of Physical Activity Consortium, whose goal is to create a multiomic map of the response to physical activity, and co-PI on the Exercise at the Limit – Inherited Traits of Endurance, a project whose goal is to identify the genetic contributors to human performance